Status:
UNKNOWN
Clinical Trial Comparing Intravenous and Oral Diclofenac and Pharmacokinetics
Lead Sponsor:
Hamad Medical Corporation
Conditions:
Pain Management
Limb Injury
Eligibility:
All Genders
18-65 years
Phase:
PHASE4
Brief Summary
NSAIDs are commonly used in the management of acute pain; Diclofenac is one from the same class. It is an amino phenyl acetic acid derivative which inhibits prostaglandin biosynthesis to produce analg...
Detailed Description
This will be a prospective, double blinded, randomized clinical trial, and it will be conducted and reported according to the consolidated standards of reporting trials group 14. Setting: The study ...
Eligibility Criteria
Inclusion
- Eligible patients are those adults (age at least 18years), presenting to HGH-ED with complaints of acute limb injury, initially evaluated by the physician.
- Inclusion criteria:
- Healthy volunteers
- Adult patients above 18-65 years of age.
- Patients with soft tissue injury/ cut wounds
- Pain score more than or equal to 4 on NRS.
- Patients weight more than or equal to 50kgs.
- If treating physician approves patient participation in the study.
- Not on any medication.
- Exclusion criteria:
- Received any analgesic within last 12 hours, on the day of visit to ED.
- Patients with fractures
- Allergic to diclofenac.
- Cardio-vascular disease, renal impairment, stroke or any other co-morbidity / chronic illness.
- Pregnancy / Nursing
- Peptic ulcers
- Bleeding disorders
- liver disease
- Bronchial asthma
Exclusion
Key Trial Info
Start Date :
January 15 2018
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
April 15 2018
Estimated Enrollment :
300 Patients enrolled
Trial Details
Trial ID
NCT03472339
Start Date
January 15 2018
End Date
April 15 2018
Last Update
March 22 2018
Active Locations (1)
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1
Isma Qureshi
Doha, Qatar, 3050