Status:

UNKNOWN

the Change of CEM and the Prognosis of Coronary Artery Disease in Real Clinical Practice

Lead Sponsor:

Lu'an Municipal Hospital

Collaborating Sponsors:

First Affiliated Hospital of Jinan University

Conditions:

Coronary Artery Disease

Eligibility:

All Genders

45-70 years

Brief Summary

The purpose of this study is to investigate the change of total cholesterol content of erythrocyte membranes (CEM) in patients with coronary artery disease treated with secondary prevention drugs, and...

Detailed Description

In this clinical trial, plasma samples, the red cells and associated clinical data of patients with coronary artery disease were collected from Department of Cardiology of Lu'an Shili Hospital and the...

Eligibility Criteria

Inclusion

  • Signed informed consent;
  • First diagnosis of CAD through CAG;
  • Aged 45-70.

Exclusion

  • Patients with severe liver or kidney damage;
  • Taking statins within the last 3 months;
  • Patients who had been diagnosed with CAD and treated with oral medication;
  • Chronic diseases of the blood system;
  • Familial hyperlipidemia patients;
  • Patients combining autoimmune disease;
  • Patients combining acute infectious disease;
  • Patients who undertaken surgery or injury;
  • Patients who combining cancer;
  • Patients who taking glucocorticoid replacement therapy;
  • Abnormal red blood cell (RBC) count (M: \<4.0 or \>5.5 × 1012/L; F: \<3.5 or \>5.0 × 1012/L) or abnormal hemoglobin (M: \<120 or \>160 g/L; F: \<110 or \>150 g/L).

Key Trial Info

Start Date :

April 1 2018

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 31 2021

Estimated Enrollment :

200 Patients enrolled

Trial Details

Trial ID

NCT03473860

Start Date

April 1 2018

End Date

December 31 2021

Last Update

March 22 2018

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