Status:
COMPLETED
Fetuin-A Phosphorylation Status in Insulin Resistance and Metabolic Syndrome
Lead Sponsor:
Auburn University
Conditions:
Obesity
Metabolic Syndrome
Eligibility:
MALE
30-65 years
Phase:
NA
Brief Summary
Fetuin-A has been identified as a novel physiological regulator of insulin action in vitro, in intact cells and in vivo in animals. Previous research has shown that circulating levels of fetuin-A were...
Detailed Description
There are several objectives of this study: (1) Quantitate phosphorylated fetuin-A levels and the daily variation in these levels in individuals with insulin resistance and metabolic syndrome; (2) Inv...
Eligibility Criteria
Inclusion
- 30 to 65 years of age
- obese (BMI \> 30 kg⋅m2 or % fat \> 30, and waist girth \> 88 cm)
- weight stable over the previous 6 months
Exclusion
- smoker
- documented cardiovascular or metabolic disease
- currently taking medication to alter lipid or glucose metabolism
- practicing regular leisure physical activity over the previous 6 months
- engaged in strenuous vocational activity over the previous 6 months
- signs or symptoms of latent heart disease
- conditions that would preclude treadmill walking
Key Trial Info
Start Date :
October 10 2007
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 31 2015
Estimated Enrollment :
42 Patients enrolled
Trial Details
Trial ID
NCT03478046
Start Date
October 10 2007
End Date
May 31 2015
Last Update
March 27 2018
Active Locations (1)
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1
Auburn University
Auburn, Alabama, United States, 36849