Status:
COMPLETED
Meal Glycaemic Index and Exercise After Gastric Bypass
Lead Sponsor:
Kirstine Nyvold Bojsen-Moeller
Collaborating Sponsors:
University of Copenhagen
Conditions:
Roux-en-Y Gastric Bypass
Obesity
Eligibility:
All Genders
20-75 years
Phase:
NA
Brief Summary
The study will evaluate postprandial glucose excursions and gut hormone secretion after ingestion of meals with different glycaemic index (GI) values (high vs low) followed by an acute bout of exercis...
Eligibility Criteria
Inclusion
- RYGB patients:
- Undergone Roux-en-Y gastric bypass (RYGB) without complications at least 12 months prior to inclusion.
- Achieved \> 50% Excess BMI Loss
- Weight stability (no fluctuations over ± 5 kg the last 3 months)
- HBA1c \< 48 mmol/mol before and after surgery without the use of anti-diabetic medication
- The participant must be able to ingest the meals
Exclusion
- Low hemoglobin levels (\< 6.5 mM)
- Pregnancy (determined by human chorionic gonadotropin (hCG) test) or breastfeeding
- Dysregulated thyroid gland affection
- The use of medication which affects heart frequency (i.e. Beta-blockers)
- Complications following RYGB consisting of dysphagia or other problems associated with ingestion of normal foods (i.e. vomit, diarrhea or strong abdominal pain).
- Control group:
- Inclusion Criteria:
- Matched with the RYGB patients on gender, age (± 5 years), menopausal state (pre- versus post-menopausal) and BMI (± 3 points).
- Weight stable ( ± 5 kg during 3 months)
- HBA1c \< 48 mmol/mol
Key Trial Info
Start Date :
March 1 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2020
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT03478098
Start Date
March 1 2018
End Date
March 1 2020
Last Update
June 15 2023
Active Locations (1)
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1
Department of Endocrinology, Hvidovre Hospital
Hvidovre, Denmark, DK-2650