Status:
COMPLETED
Platelet Rich Plasma Versus Placebo for the Treatment of Greater Trochanteric Pain Syndrome (HiPPO Trial)
Lead Sponsor:
Northumbria Healthcare NHS Foundation Trust
Conditions:
Greater Trochanteric Pain Syndrome
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Greater Trochanteric Pain Syndrome (GTPS), also known as Trochanteric Bursitis, is a painful condition predominantly affecting middle aged women. It is characterised by pain in the lateral hip exacerb...
Detailed Description
1. What is the problem being addressed? Greater trochanteric pain syndrome (GTPS), also known as trochanteric bursitis, is a painful condition characterised by pain around the greater trochanter usual...
Eligibility Criteria
Inclusion
- Over 18 years of age
- Symptoms consistent with GTPS present for at least 6 months
- Radiological diagnosis of GTPS using MRI, or ultrasound scan if MRI contraindicated
- Failed conservative management in any other care setting
- Patient is willing and able to provide written informed consent.
Exclusion
- Lacks capacity to provide consent
- Has hip joint osteoarthritis requiring treatment on a plain radiograph
- Presence of confounding pathologies of the hip MRI
- Any extensive surgery or deformity of the hip on X-ray.
- Presence of systemic disorders -coagulopathy, active infection, immune system disorders, peripheral neuropathy, malignancy, unresolved fractures.
- Had any surgical treatment specifically targeted at GTPS e.g. bursectomy/Ilio-tibial band lengthening
- Pregnancy
- Anti-coagulant therapy eg warfarin, rivaroxaban, apixaban, dabigatran
- Haemaglobin \<10g/dL or platelets \< 150,000/ul
- Unable to safely stop anti-platelet/NSAID medications eg. Recent cardiac stenting
- Has lumbar-sacral spine pathology or a recent history of acute hip trauma
- Has a recent history of acute sciatica
- Is not able to attend or comply with treatment or follow-up scheduling
- Participates in any other clinical trial
Key Trial Info
Start Date :
September 3 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 3 2022
Estimated Enrollment :
84 Patients enrolled
Trial Details
Trial ID
NCT03479190
Start Date
September 3 2018
End Date
April 3 2022
Last Update
March 24 2023
Active Locations (1)
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1
Northumbria Healthcare NHS Trust
Newcastle upon Tyne, TYNE and WEAR, United Kingdom