Status:
COMPLETED
Glycemic Control and Endothelial Function in Patients With Type 2 Diabetes
Lead Sponsor:
Karolinska Institutet
Conditions:
Type 2 Diabetes Mellitus
Eligibility:
All Genders
Up to 80 years
Brief Summary
Study objective To evaluate the mechanism behind endothelial dysfunction in patients with type 2 diabetes in relation to the level of glycaemic control. Primary endpoint: Change in endothelium depend...
Detailed Description
The study is performed on one group of patients with type 2 diabetes and one group of age-matched healthy controls Inclusion criteria: 1. Type 2 diabetes 2. Poor glycaemic control defined as a mean ...
Eligibility Criteria
Inclusion
- Type 2 diabetes
- Poor glycaemic control defined as a mean day blood glucose \>12 mmol/L.
Exclusion
- Age \>80 years.
- HbA1c \<70 mmol/mol
- Myocardial infarction/unstable angina within 6 weeks prior to the study.
- Treatment with oral anticoagulants (Warfarin or New oral anticoagulants)
- Raynaud's phenomenon, peripheral vasculopathies, arterial shunting or other vascular surgery of the study arm.
- Any concomitant disease or condition that may interfere with the possibility for the patient to comply with or complete the study protocol.
- Participant in an ongoing study.
- Unwillingness to participate following oral and written information.
Key Trial Info
Start Date :
January 1 2016
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
July 31 2019
Estimated Enrollment :
16 Patients enrolled
Trial Details
Trial ID
NCT03480945
Start Date
January 1 2016
End Date
July 31 2019
Last Update
February 21 2020
Active Locations (1)
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1
Karolinska Institutet, Karolinska University Hospital
Stockholm, Sweden, 17176