Status:
RECRUITING
Ischemic Conditioning During Air tRansport Save penUmbral Tissue
Lead Sponsor:
Enrique Leira
Conditions:
Acute Stroke
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
The purpose of this study is to demonstrate the feasibility of performing remote limb ischemic conditioning (RLIC) using the Doctormate device, a special blood pressure device used to perform RLIC, on...
Detailed Description
In this study, 15 subjects presenting to a community hospital with signs and symptoms of ischemic stroke due to large vessel occlusion, transported to a comprehensive stroke center by aircew will rece...
Eligibility Criteria
Inclusion
- Age ≥18 and ≤ 80 years
- Suspected acute ischemic stroke with symptoms suggestive of large vessel occlusion (aphasia, agnosia, neglect, visual field cut, and gaze preference).
- Patient screened for rtPA, and rtPA administered if eligible
- Subject or legally authorized representative able to provide consent at the time of the assessment
- NIHSS 6-20
Exclusion
- Any intracranial hemorrhage (parenchymal, subarachnoid, subdural, epidural) on CT scan at the community hospital
- History of upper or lower extremity ischemia, known subclavian, brachial artery, iliac or femoral artery stenosis, subclavian steal syndrome, any upper or lower extremity soft tissue, orthopedic or vascular injury, or mastectomy or other procedure that may contraindicate taking blood pressure or having a cuff on the arm or leg for the conditioning treatment
- History of diabetes mellitus
- Enrollment in another clinical trial
- Patient incarcerated
- Pregnancy. Patients ages 18-55 will need to have a negative urine or blood based pregnancy test.
- Agitation deemed unsafe for ischemic preconditioning testing.
- Arteriovenous fistula in upper limb
Key Trial Info
Start Date :
June 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2026
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT03481205
Start Date
June 1 2020
End Date
December 31 2026
Last Update
November 7 2025
Active Locations (1)
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1
University of Iowa
Iowa City, Iowa, United States, 52242