Status:

COMPLETED

The Effect of Dietary Lauric Acid on the Production of the LRH-1 Ligand, Dilauroylphosphatidylcholine

Lead Sponsor:

Cornell University

Conditions:

Diet Modification

Eligibility:

All Genders

18-50 years

Phase:

NA

Brief Summary

A phosphatidylcholine species enriched with lauric acid at both the sn-1 and sn-2 positions, dilauroylphosphatidylcholine (DLPC), was recently identified as a ligand for the nuclear receptor, liver re...

Detailed Description

A phosphatidylcholine species enriched with lauric acid at both the sn-1 and sn-2 positions, dilauroylphosphatidylcholine (DLPC), was recently identified as a ligand for the nuclear receptor, liver re...

Eligibility Criteria

Inclusion

  • Willingness to comply with the study protocol
  • Ability to overnight fast
  • Willingness to donate blood
  • 'generally healthy'

Exclusion

  • self-reported regular consumption of tropical oils or supplements containing lauric acid
  • self-reported food allergies to shake ingredients
  • medical conditions where blood draws or fasting may be contraindicated
  • major gastrointestinal conditions, such as inflammatory bowel disease

Key Trial Info

Start Date :

March 19 2018

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 22 2018

Estimated Enrollment :

10 Patients enrolled

Trial Details

Trial ID

NCT03481608

Start Date

March 19 2018

End Date

April 22 2018

Last Update

March 22 2022

Active Locations (1)

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1

Human Metabolic Research Unit, Cornell University

Ithaca, New York, United States, 14853