Status:
COMPLETED
Remote Ischemic Conditioning in Patients With Acute Stroke (RESIST)
Lead Sponsor:
Grethe Andersen
Collaborating Sponsors:
Danish National Research Foundation
Central Denmark Region
Conditions:
Stroke, Acute
Ischemic Stroke
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Our primary aim is to investigate whether remote ischemic conditioning (RIC) as an adjunctive treatment can improve long-term recovery in acute stroke patients as an adjunct to standard treatment.
Detailed Description
Stroke is the second-leading cause of death worldwide and a leading cause of serious, long-term disability. The most common type is acute ischemic stroke (AIS) which occurs in 85% of cases. Acute cere...
Eligibility Criteria
Inclusion
- Male and female patients (≥ 18 years)
- Prehospital putative stroke (Prehospital Stroke Score, PreSS \>= 1)
- Onset of stroke symptoms \< 4 hours before RIC/Sham-RIC
- Independent in daily living before symptom onset (mRS ≤ 2)
Exclusion
- Intracranial aneurisms, intracranial arteriovenous malformation, cerebral neoplasm or abscess
- Pregnancy
- Severe peripheral arterial disease in the upper extremities
- Concomitant acute life-threatening medical or surgical condition
- Arteriovenous fistula in the arm selected for RIC
Key Trial Info
Start Date :
March 15 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 3 2023
Estimated Enrollment :
1500 Patients enrolled
Trial Details
Trial ID
NCT03481777
Start Date
March 15 2018
End Date
February 3 2023
Last Update
January 27 2025
Active Locations (4)
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1
Department of Neurology Aarhus University Hospital
Aarhus, Danmark, Denmark, DK-8000
2
Aalborg University Hospital
Aalborg, DK, Denmark, 9000
3
Odense University Hospital
Odense, DK, Denmark, 5000
4
Department of Neurology Regional Hospital West Jutland
Holstebro, Denmark, DK-7500