Status:

COMPLETED

The Effect of Fontan Fenestration Closure on Hepatic Stiffness

Lead Sponsor:

Boston Children's Hospital

Conditions:

Single-ventricle

Hepatic Congestion

Eligibility:

All Genders

Brief Summary

The overarching goal of this project is to discern how closure of Fontan fenestrations in patients with single ventricle heart disease will affect hepatic congestion, a major determinant of chronic li...

Detailed Description

Methods Eligible patients will be contacted in advance of hospitalization for catheterized fenestration closure to introduce goals of study and review risks and benefits of participation. At the time ...

Eligibility Criteria

Inclusion

  • Functional Single ventricle patients after a fenestrated lateral tunnel or extra-cardiac Fontan
  • Patients scheduled for possible fenestration closure in the catheterization laboratory
  • Informed consent has been obtained

Exclusion

  • Patients with spontaneous closure of Fenestration
  • Ascites
  • Ventilatory requirement
  • Implantable cardiac device
  • Ongoing inotropic support
  • Pregnancy
  • Inability to tolerate four hour pre-procedure fasting

Key Trial Info

Start Date :

May 29 2018

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

June 30 2022

Estimated Enrollment :

16 Patients enrolled

Trial Details

Trial ID

NCT03481985

Start Date

May 29 2018

End Date

June 30 2022

Last Update

April 19 2023

Active Locations (1)

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1

Boston Children's Hospital

Boston, Massachusetts, United States, 02115