Status:

UNKNOWN

Evaluation of Lung Nodule Detection With Artificial Intelligence Assisted Computed Tomography in North China

Lead Sponsor:

Peking University People's Hospital

Collaborating Sponsors:

Lu'an Municipal Hospital

North China Petroleum Bureau General Hospital

Conditions:

Solitary Pulmonary Nodule

Multiple Pulmonary Nodules

Eligibility:

All Genders

40+ years

Brief Summary

Lung cancer is one of the leading cause of cancer related death in China. Lung cancer screening with low-dose computed tomography was considered as a better approach than radiography. However, the rol...

Detailed Description

Lu'an Municipal Hospital and North China Petroleum Bureau General Hospital initialed the lung cancer screening by LDCT a few years ago. People living in North China who are administrated by these hosp...

Eligibility Criteria

Inclusion

  • Aged 40 years or older
  • Routinely conducting chest CT scan at a low-dose setting (120kVp, 40-80mA, slice thickness of 1.25 mm or less) yearly in Lu'an Municipal Hospital and North China Petroleum Bureau General Hospital in at least the past 4 years up to December 2017, willing to continue routine yearly LDCT scan.
  • Chest CT data are available for DICOM format.
  • Signed Informed Consent Form.

Exclusion

  • Pregnant woman and the disabled
  • Past thoracic surgery history, except for diagnostic thoracoscopy
  • Poor physical status without sufficient respiratory reserve to undergo lobectomy if necessary
  • Shortened life expectancy less than 10 years
  • Malignant tumor history within the past 5 years, except for the following conditions: cured skin basal cell carcinoma, superficial bladder carcinoma. and uterine cervix cancer in situ.
  • Past history of interstitial lung disease, pulmonary bulla and lung tuberculosis.
  • Other circumstances which is deemed inappropriate for enrollment by the researchers.

Key Trial Info

Start Date :

April 1 2018

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 1 2021

Estimated Enrollment :

5000 Patients enrolled

Trial Details

Trial ID

NCT03487952

Start Date

April 1 2018

End Date

December 1 2021

Last Update

April 4 2018

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