Status:

UNKNOWN

Adjunctive Use of Salvadora Persica in Chronic Periodontitis

Lead Sponsor:

King Saud University

Collaborating Sponsors:

Ziauddin University

Conditions:

Chronic Periodontitis

Eligibility:

All Genders

30-65 years

Phase:

EARLY_PHASE1

Brief Summary

A randomized controlled triple blinded study to evaluate the effectiveness of Salvadora Persic (SP) as an adjunct to Scaling and Root Planing (SRP) in chronic periodontitis by comparing the basic para...

Detailed Description

Sixty-six subjects with untreated, moderate-to-severe chronic periodontitis will be selected by convenience sampling. The participants will be randomly divided into 2 groups: 1. Test group: SRP + SP ...

Eligibility Criteria

Inclusion

  • Subjects who are \>30 years old
  • Minimum of 20 teeth , excluding third molars
  • Systemically healthy patients with moderate (PD of 5 to 6 mm or clinical attachment loss CAL of 4 to 6 mm) or deep pockets (PD ≥7mm or CAL of 6 to 9 mm) and vertical bone loss ≥3 mm on intraoral periapical radiographs (Armitage 1999)

Exclusion

  • Presence of systemic conditions that could modify the progression of periodontitis such as diabetes mellitus, metabolic syndrome, cardiovascular disease or immunologic disorders
  • Systemic antimicrobials in the previous 6 months
  • Aggressive periodontitis
  • Pregnancy or lactation
  • Inability to provide informed consent

Key Trial Info

Start Date :

April 1 2019

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

October 1 2019

Estimated Enrollment :

66 Patients enrolled

Trial Details

Trial ID

NCT03749369

Start Date

April 1 2019

End Date

October 1 2019

Last Update

March 1 2019

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