Status:

COMPLETED

Stoma Closure and Reinforcement Trial

Lead Sponsor:

Dartmouth-Hitchcock Medical Center

Collaborating Sponsors:

Hitchcock Foundation

Conditions:

Colon Cancer

Rectal Cancer

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Hernia formation at sites of ostomy closure is a common complication. The investigator believes that using evidence based hernia repair techniques as a preventive measure during closure of ostomies wi...

Eligibility Criteria

Inclusion

  • Age \> 18years
  • Patient is undergoing closure of loop ileostomy
  • Patient has a diagnosis of left sided colon or rectal cancer treated with resection and diverting loop ileostomy
  • Patient has been evaluated by a qualified surgeon and found to be a suitable candidate for surgery

Exclusion

  • Pre-existing systemic infection at the time of ileostomy takedown
  • Cirrhosis, chronic renal failure requiring dialysis, or collagen disorder
  • On current immunosuppression (anti-tumor necrosis factor (TNF) agents, chemotherapy, or prednisone \>10mg/day)
  • Previous abdominal hernia repair with mesh placement
  • Concurrent procedures in addition to closure of diverting loop ileostomy
  • Ileostomy closure not completed through the previous stoma site (i.e. those requiring exploratory laparotomy for closure)

Key Trial Info

Start Date :

January 1 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 1 2023

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT03750461

Start Date

January 1 2019

End Date

February 1 2023

Last Update

February 22 2023

Active Locations (1)

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Dartmouth Hitchcock Medical Center

Lebanon, New Hampshire, United States, 03756