Status:
COMPLETED
Effect of Aging on Cortical Excitability and Motor Learning
Lead Sponsor:
VA Office of Research and Development
Conditions:
Aging
Eligibility:
All Genders
50-85 years
Phase:
NA
Brief Summary
The objective of the current proposal is to identify 1) how aging-related changes in GABAergic cortical inhibition affect motor performance, and 2) how aerobic exercise may improve inhibitory function...
Detailed Description
The current proposal seeks quantify neural inhibition using magnetic resonance spectroscopy (MRS) and transcranial magnetic stimulation (TMS) in older Veterans to identify how each measures contribute...
Eligibility Criteria
Inclusion
- living persons aged 50-85
Exclusion
- unmanaged diabetes
- participants completing vigorous exercise per week
- participants whose profession requires vigorous physical labor
- contraindication to magnetic resonance imaging
Key Trial Info
Start Date :
March 4 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 30 2024
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT03750903
Start Date
March 4 2019
End Date
September 30 2024
Last Update
April 3 2025
Active Locations (1)
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1
Atlanta VA Medical and Rehab Center, Decatur, GA
Decatur, Washington, United States, 30033-4004