Status:

TERMINATED

Microbiome Alterations in IL10RA-deficient Patients After HSCT

Lead Sponsor:

Children's Hospital of Fudan University

Conditions:

Inflammatory Bowel Diseases

Microbiota

Eligibility:

All Genders

1-6 years

Brief Summary

To elucidate the longitudinal development of intestinal microbiota in patients with IL10RA deficiency after hematopoietic stem cell transplantation (HSCT). The investigators planned to collect fecal s...

Detailed Description

Hematopoietic stem cell transplantation is considered the only curative therapy for patients with interleukin-10 receptor-A(IL10RA) deficiency. The investigators aimed to collect the fecal samples of ...

Eligibility Criteria

Inclusion

  • IL10RA gene mutations;
  • Eligible for hematopoietic stem cell transplantation.

Exclusion

  • Unwilling to participate.

Key Trial Info

Start Date :

October 1 2017

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

February 28 2020

Estimated Enrollment :

13 Patients enrolled

Trial Details

Trial ID

NCT03752372

Start Date

October 1 2017

End Date

February 28 2020

Last Update

August 12 2020

Active Locations (1)

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1

Children's hospital of Fudan university

Shanghai, Shanghai Municipality, China, 201102