Status:

COMPLETED

Stress Systems and Psychotherapy in Depression

Lead Sponsor:

Freie Universität Berlin

Conditions:

Major Depressive Episode

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

Dysregulation of the hypothalamus-pituitary-adrenal (HPA) axis as well as maladaptive activation of the autonomic nervous system (ANS) are discussed as relevant factors in the development of a major d...

Detailed Description

Recruitment: Patients will be recruited from an ongoing project providing an internet-based cognitive behavioral intervention for patients suffering from mild to moderate depression. Protocol: In t...

Eligibility Criteria

Inclusion

  • Current major depressive episode (F32.0, F32.1, F33.0, F33.1)
  • Agreement to participate in the study
  • At least 18 years of age

Exclusion

  • Diagnosis of schizophrenia, schizotypal and delusional disorders (F20-F29)
  • Acute suicidal patients
  • Acute manic episode
  • Substance related abuse or addiction
  • Pregnancy or lactation
  • Chronic somatic diseases
  • Severe somatic diseases (e.g., endocrinological, neurological, autoimmune diseases)
  • Glucocorticoid medication intake during the last six months
  • Concurrent psychotherapeutic treatment

Key Trial Info

Start Date :

November 20 2018

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 6 2020

Estimated Enrollment :

42 Patients enrolled

Trial Details

Trial ID

NCT03752853

Start Date

November 20 2018

End Date

August 6 2020

Last Update

October 23 2020

Active Locations (1)

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Freie Universitaet Berlin

Berlin, Germany, 14195

Stress Systems and Psychotherapy in Depression | DecenTrialz