Status:
UNKNOWN
Effects of PEEP on Parameters of Tissue Perfusion in Patients Post Cardiac Surgery
Lead Sponsor:
Federal University of São Paulo
Collaborating Sponsors:
Vanessa Marques Ferreira
Conditions:
Coronary Artery Disease
Coronary Artery Bypass Grafting
Eligibility:
All Genders
18-75 years
Phase:
NA
Brief Summary
Pulmonary dysfunction is a condition inherent in cardiac surgery because of various interventions, such as general anesthesia, a median sternotomy, cardiopulmonary bypass and establishment of internal...
Detailed Description
This is a prospective, randomized study and will be performed on patients who accept coronary artery bypass grafting with cardiopulmonary bypass, the conscious openness to participate in the study. Ag...
Eligibility Criteria
Inclusion
- elective and isolated CABG, ejection fraction greater than 40%
Exclusion
- patients with a diagnosis of pulmonary disease, emergency surgery and mechanical ventilation prior to surgery.
- Postoperative patients who had radiological abnormalities suggestive of pneumothorax, atrial or ventricular arrhythmias, electrical ischemic changes on ECG, pulse pressure variation of more than 13, hemodynamic instability characterized by mean arterial pressure less than 60 mmHg, nor epinephrine greater than 0.5 mcg/Kg/ min and the presence of increased bleeding through the drains (greater than 2 ml \\ kg \\ h) the protocol was discontinued and the patient excluded from the study.
Key Trial Info
Start Date :
January 1 2012
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2019
Estimated Enrollment :
125 Patients enrolled
Trial Details
Trial ID
NCT03753022
Start Date
January 1 2012
End Date
December 1 2019
Last Update
November 29 2018
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