Status:
UNKNOWN
The Effects of Transcranial Direct Current Stimulation on Executive Function in People With Mild to Moderate Dementia
Lead Sponsor:
The Hong Kong Polytechnic University
Conditions:
Dementia
Executive Function
Eligibility:
All Genders
65-90 years
Phase:
NA
Brief Summary
To study the effects of transcranial direct current stimulation on executive function in people with mild to moderate dementia
Detailed Description
Extensive research had shown executive dysfunction in people with dementia (PWD) is associated with functional abnormalities in prefrontal regions such as the right inferior frontal gyrus (Right IFG) ...
Eligibility Criteria
Inclusion
- PWD must be aged at least 65 years or above when informed consent is obtained in the presence of his / her first degree relatives.
- PWD must meet criteria of DSM-V for dementia as well as for historical diagnosis of dementia.
- PWD must have a Chinese MoCA score \> 19 (mild to moderate cognitive deficits) at screening.
- Subjects (both PWD and HC) must be physically healthy, and must be able to understand and be willing to sign the informed consent document
Exclusion
- Subject with major neurological illness.
- Subject with other diagnosed psychiatric disorders
- Subjects reported with history of substance abuse, which including alcohol, drugs or any medication which is indicative of chronic abuse.
- Failures to comply with the study protocol or to follow the instructions.
- Self-reported with known skin diseases or skin allergy history.
- Self-reported with metallic implants, dentures
- Self-reported with history of claustrophobia. (This is excluded because subject needs to stay in a quiet room with the head-mounted fNIRS and tDCS, which may elicit their feeling of anxiety)
Key Trial Info
Start Date :
June 1 2019
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
October 20 2021
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT03753191
Start Date
June 1 2019
End Date
October 20 2021
Last Update
October 22 2020
Active Locations (1)
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1
The Hong Kong Polytechnic University
Hong Kong, Hong Kong