Status:

COMPLETED

Physical Training Induced Plasticity of Motor Control Mechanisms in Parkinson's Disease Patients

Lead Sponsor:

Wroclaw University of Health and Sport Sciences

Collaborating Sponsors:

Wroclaw Medical University

University School of Physical Education, Krakow, Poland

Conditions:

Parkinson Disease

Physical Activity

Eligibility:

All Genders

55-75 years

Phase:

NA

Brief Summary

There are experimental evidences of the important role of exercise in the PD, that induces similar effects to pharmacotherapy. So far, the mechanisms of the impact of these changes on the brain subcor...

Detailed Description

I. Research Project Objectives Aim 1. To characterize an influence of 8-week HIIT cycle on neurophysiological functions (NPFs) of: (i) motor cortical structures, (that are critically dependant on the...

Eligibility Criteria

Inclusion

  • for PD patients: age 55-75 years-old; diagnosis of idiopathic PD; and modified Hoehn and Yahr stages between 1.5 and 3
  • for healthy controls: lack of neurological disorders

Exclusion

  • for PD patients: (i) presence of other neurological disorders, (2) any cardiovascular and respiratory system restrictions and/or motor deficits that could limit performance in high-speed pedaling on a cycle ergometer or in the conventional physical therapy and (3) practicing any regular physical activity except for physical therapy for PD
  • for healthy controls: presence of neurological disorders

Key Trial Info

Start Date :

November 8 2012

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 9 2016

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT03753503

Start Date

November 8 2012

End Date

November 9 2016

Last Update

December 3 2018

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