Status:
COMPLETED
Effect of Nicotinamide Riboside and Pterostilbene Supplementation on Muscle Regeneration in Elderly Humans
Lead Sponsor:
University of Aarhus
Collaborating Sponsors:
University of Copenhagen
Conditions:
Muscle Injury
Eligibility:
All Genders
55-80 years
Phase:
NA
Brief Summary
Successful skeletal muscle regeneration depends on a functional pool of muscle stem cells, termed satellite cells (SC). SC are in a quiescent state throughout adulthood, but undergo multiple cycles of...
Detailed Description
14 days after start of placebo or NR/PT (500/100 mg twice daily) supplementation a muscle damage will induced in the m. vastus lat. by electric stimulation combined with eccentric work in a dynamomete...
Eligibility Criteria
Inclusion
- Written signed consent
- Age: 55-80
- BMI: 20-28 (kg/(m2))
- Non-smoker
Exclusion
- Endocrine disease, neurological or muscle disease
- Other severe disease
- High daily activity level (\>30 min / day)
Key Trial Info
Start Date :
February 12 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2020
Estimated Enrollment :
32 Patients enrolled
Trial Details
Trial ID
NCT03754842
Start Date
February 12 2019
End Date
September 1 2020
Last Update
November 5 2020
Active Locations (1)
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1
Aarhus University Hospital
Aarhus N, Denmark, 8200