Status:

RECRUITING

Clinical Trial of an MRI Based Patient Specific Focal Knee Resurfacing Implant

Lead Sponsor:

Universitaire Ziekenhuizen KU Leuven

Conditions:

Cartilage Damage

Knee Injuries

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The goal of this study is to evaluate the efficacy, safety and performance of the Episealer® device in a sample size of 30 patients and on the long term (10 years follow-up).

Detailed Description

Lesions in the cartilage are common disorders. In the knee, cartilage lesions are found in over 50 % of all arthroscopies, where 25 % of these are of focal character and the majority are found in the ...

Eligibility Criteria

Inclusion

  • Subjects with a focal cartilage lesion of the distal femur in which biological surgical methods have failed or are not eligible
  • Minimal age 18 years (Preferred age group \>40 years)
  • Suitable for implant, to be determined by analysis of MRI imaging. Suitability is set by the size and location of the lesion.
  • Informed consent

Exclusion

  • Under age (\<18yrs)
  • Active or recent (\<1 yr) septic arthritis of the involved knee
  • Associated symptomatic untreated ligamentary or meniscal pathology in the involved knee
  • (Severe) osteoarthritis in the involved or other compartments of the involved knee
  • Severe osteoporosis
  • MRI not possible (eg. due to pacemaker)
  • Marked valgus- or varus alignment (\>6 degrees)

Key Trial Info

Start Date :

September 20 2018

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2034

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT03755388

Start Date

September 20 2018

End Date

December 1 2034

Last Update

November 8 2024

Active Locations (1)

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UZ Leuven

Leuven, Vlaams-Brabant, Belgium, 3000