Status:

COMPLETED

Pupil Dilation for Treatment of IFIS

Lead Sponsor:

Denver Health and Hospital Authority

Conditions:

Intraoperative Floppy Iris Syndrome

Eligibility:

All Genders

18-100 years

Phase:

PHASE2

Brief Summary

A novel intervention for targeting the treatment of Intraoperative Floppy Iris Syndrome.

Detailed Description

This study explores the effects that medication can have on increasing pupil dilation. Pupil dilation size is important for operative eye procedures. Decreased pupil size is related to increased compl...

Eligibility Criteria

Inclusion

  • 1\. Adults (18 years old or greater) 3. History of having taken, or currently taking any systemic alpha blocker 2. Ability to consent themselves 3. Ability to apply eye drops themselves TID for 7 days

Exclusion

  • Subjects with untreated hypertension or baseline BP \>160
  • Subjects with Thyrotoxicosis
  • Pregnant women or women trying to conceive
  • Prisoners
  • Inability consent
  • Subjects with anatomical narrow angles or who have never had a dilated eye exam
  • Subjects currently prescribed brimonidine tartrate for glaucoma
  • Subjects who take topical or systemic alpha agonists
  • Patients who take monoamine oxidase (MAO) inhibitors
  • Patients with known severe cardiovascular disease

Key Trial Info

Start Date :

January 4 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 25 2020

Estimated Enrollment :

13 Patients enrolled

Trial Details

Trial ID

NCT03760185

Start Date

January 4 2019

End Date

September 25 2020

Last Update

April 20 2022

Active Locations (1)

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Denver Health

Denver, Colorado, United States, 80204