Status:
COMPLETED
Optimization of VIM Targeting in Essential Tremor Surgery
Lead Sponsor:
University Hospital, Bordeaux
Conditions:
Essential Tremor
Eligibility:
All Genders
18-75 years
Phase:
NA
Brief Summary
Deep brain stimulation (DBS) for essential tremor is based on the intermedius ventralis nucleus of the thalamus (VIM) stimulation. This structure is however very difficult to target, as it remains inv...
Detailed Description
The intermedius ventralis nucleus of the thalamus (VIM), which represents the target for deep brain stimulation (DBS) in essential tremor, still remains invisible on 1,5 tesla MRI (the only magnetic f...
Eligibility Criteria
Inclusion
- Severe essential tremor despite the optimal medical management
- Age between 18 and 75 years
- Normal MRI scan
- Mattis Dementia Rating Scale (MDRS) score ≥ 130
- Affiliation to the social security
- Signed informed consent
Exclusion
- Depression (Beck Depression Inventory scale \> 20)
- Contra-indication to surgery or general anesthesia
- Cerebral atrophy on MRI scan
- Pregnant or breastfeeding women
Key Trial Info
Start Date :
March 18 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 29 2023
Estimated Enrollment :
22 Patients enrolled
Trial Details
Trial ID
NCT03760406
Start Date
March 18 2019
End Date
August 29 2023
Last Update
February 25 2025
Active Locations (2)
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1
CHU de Bordeaux
Bordeaux, France, 33076
2
Hospices Civils de Lyon
Bron, France, 69500