Status:
UNKNOWN
Post- End- Expiratory Pressure Affect the Alveolar Heterogeneity in Moderate and Sever ARDS Patients
Lead Sponsor:
Southeast University, China
Conditions:
Ards
Eligibility:
All Genders
18-80 years
Brief Summary
This study try to use EIT ( Electronic impedance tomography ) to evaluate the alveolar heterogeneity and use trans-pulmonary pressure and stain to evaluate the lung injury . The study use these method...
Detailed Description
ARDS(Acute respiratory distress syndrome )is common in patients suffering Sepsis, trauma, burning and other sever condition and characterized by diffuse alveolar damage and alveolar heterogeneity.ARDS...
Eligibility Criteria
Inclusion
- Age≥18 or\<80；
- Moderate or sever ARDS in 2012 \<Berlin definition\>;
- Applied mechanical ventilation;
- Consent signed.
Exclusion
- Asthma or COPD；
- Cardiogenic edema；
- Sever neutropenia(\<500/mm3)；
- Hemodynamic astatic: DOPA or Dobutamine \>15 µg/kg/ min; NE \> 15ug /min；
- GCS coma score ≤12；
- Thoracic injury or surgery patients contradict EIT ；
- Refuse to join in trail；
- Included in other clinical trail。
Key Trial Info
Start Date :
September 1 2018
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 30 2023
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT03763890
Start Date
September 1 2018
End Date
December 30 2023
Last Update
July 19 2022
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Nanjing Zhong-Da Hospital
Nanjing, Jiangsu, China, 210009