Status:

COMPLETED

Utility of a Novel Dd-cfDNA Test to Detect Injury in Renal Post-Transplant Patients

Lead Sponsor:

Qure Healthcare, LLC

Collaborating Sponsors:

Natera, Inc.

Conditions:

Transplant;Failure,Kidney

Eligibility:

All Genders

Phase:

NA

Brief Summary

Detecting allograft injury and rejection is critical to preventing graft loss. The current standard of care (SoC) relies on serum creatinine (SC) and biopsy to monitor for and identify kidney injury e...

Detailed Description

Five-year kidney allograft survival rates are estimated to be as low as 71.6%. A leading cause for the high prevalence of graft loss is the delay in detecting allograft injury from active rejection, w...

Eligibility Criteria

Inclusion

  • A minimum of 2 years post-residency but no more than 40 years in practice
  • Board-certified in internal medicine
  • Completion of a nephrology fellowship
  • In a private solo or multi-group practice
  • Minimum threshold of 5 post-kidney transplant (KT) patients currently seen monthly
  • Informed, signed and voluntarily consented to be in the study

Exclusion

  • Not board certified in internal medicine
  • Have practiced as a board-certified physician for less than 2 or greater than 40 years
  • See \<5 post-transplant patients monthly
  • Non-English speaking
  • Unable to access the internet

Key Trial Info

Start Date :

November 5 2018

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 7 2019

Estimated Enrollment :

175 Patients enrolled

Trial Details

Trial ID

NCT03765203

Start Date

November 5 2018

End Date

January 7 2019

Last Update

September 16 2020

Active Locations (1)

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1

QURE Healthcare

San Francisco, California, United States, 94109