Status:

COMPLETED

Bone Tissue Engineering With Dental Pulp Stem Cells for Alveolar Cleft Repair

Lead Sponsor:

Hospital Sirio-Libanes

Collaborating Sponsors:

Ministry of Health, Brazil

Conditions:

Cleft Lip and Palate

Eligibility:

All Genders

7-12 years

Phase:

PHASE3

Brief Summary

Iliac crest autogenous bone graft is accepted as the most effective method for secondary alveolar cleft repair. However this method is associated with complications. As an alternative, mesenchymal ste...

Eligibility Criteria

Inclusion

  • non syndromic unilateral cleft lip and palate;
  • age between 7 and 12 years;
  • to have the jaw aligned and ready to receive the graft.

Exclusion

  • previous surgery to correct the alveolar cleft;
  • have the canine erupted before grafting;
  • incomplete orthodontic treatment;
  • incomplete CT scan documentation.

Key Trial Info

Start Date :

April 5 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 15 2019

Estimated Enrollment :

62 Patients enrolled

Trial Details

Trial ID

NCT03766217

Start Date

April 5 2019

End Date

December 15 2019

Last Update

May 13 2020

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Hospital Sírio-Libanes

São Paulo, Brazil, 01308-050