Status:

COMPLETED

A Research Study of How Different Amounts of a New Medicine NNC0148-0287 C (Insulin 287) Works on the Blood Sugar of People Who Are Japanese With Type 1 Diabetes When Given Once a Week

Lead Sponsor:

Novo Nordisk A/S

Conditions:

Diabetes Mellitus, Type 1

Eligibility:

All Genders

20-64 years

Phase:

PHASE1

Brief Summary

This study will look at how insulin 287 works, if it is safe and the side effects in people who are Japanese with type 1 diabetes. The study will test how insulin goes through your blood, how long it ...

Eligibility Criteria

Inclusion

  • Male or female, Japanese subjects, aged 20 - 64 years (both inclusive) at the time of signing informed consent.
  • Diagnosed with type 1 diabetes mellitus greater than or equal to 1 year prior to the day of screening.
  • Current daily basal insulin treatment greater than or equal to 0.2 U/kg/day.
  • Body mass index between 18.5 and 28.0 kg/m\^2 (both inclusive).
  • HbA1c less than or equal to 9.0%.

Exclusion

  • History or presence of any clinically relevant respiratory, metabolic, renal, hepatic, gastrointestinal or endocrinological conditions (except conditions associated with diabetes mellitus).
  • Female who is pregnant, breast-feeding or intends to become pregnant or is of child-bearing potential and not using adequate contraceptive methods.
  • Known or suspected hypersensitivity to trial products or related products

Key Trial Info

Start Date :

December 7 2018

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 9 2019

Estimated Enrollment :

24 Patients enrolled

Trial Details

Trial ID

NCT03766854

Start Date

December 7 2018

End Date

December 9 2019

Last Update

March 8 2021

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Novo Nordisk Investigational Site

Fukuoka, Japan, 812-0025