Status:
COMPLETED
Peripheral Nerve Block and Topiramate in the Treatment of Medication Overuse Headaches
Lead Sponsor:
Ataturk University
Conditions:
Medication Overuse Headache
Chronic Migraine, Headache
Eligibility:
All Genders
15+ years
Phase:
NA
Brief Summary
Purpose: In this study, the investigators compared the effectiveness of peripheral nerve block (greater occipital nerve block with supratrochlear nerve block) versus topiramate as detoxification thera...
Eligibility Criteria
Inclusion
- Chronic migraine diagnosis according to International Classification of Headache-2 Disorders (ICHD)
- w/o pregnancy or breastfeeding.
- w/o acute or chronic psychiatric disorders.
- w/o nephrolithiasis.
- w/o medication of anticoagulant and antiaggregant.
- w/o allergy to topiramate or bupivacaine.
- w/o prophylaxis within the last three months with any of; propranolol, nebivolol, topiramate, valproate, venlafaxine, duloxetine, amitriptyline, flunarizine.
- w/o previous history of peripheral nerve block, botulinum toxin or acupuncture.
- w/o history of multiple sclerosis, movement disorders, epilepsy, stroke, and tumor.
- J-w/o chronic systemic diseases including hypertension, cardiac insufficiency, diabetes, pulmonary disease, kidney disease, liver disease, and peripheral arterial disease.
Exclusion
- Lost to follow up within the pretreatment period during the detoxification therapy after the detoxification therapy
- could not tolerate the peripheral nerve block or topiramate
Key Trial Info
Start Date :
March 1 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 31 2019
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT03767062
Start Date
March 1 2019
End Date
March 31 2019
Last Update
January 22 2020
Active Locations (1)
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1
Mustafa Ceylan
Erzurum, Turkey (Türkiye), 25000