Status:

UNKNOWN

Chen's U-Suture Technique for Pancreaticojejunostomy Following Pancreaticoduodenectomy

Lead Sponsor:

Chen Xiaoping

Conditions:

Pancreaticoduodenectomy

Eligibility:

All Genders

18-75 years

Phase:

NA

Brief Summary

To date, pancreaticoduodenectomy (PD) is the only recognized potentially curative therapy for malignant neoplasms located in the peri-ampullary region, and is increasingly being used for the treatment...

Detailed Description

This is a multicentre, randomized, parallel-group controlled, clinical trial to evaluate the effect and safety of Chen's U-Suture technique for pancreaticojejunostomy following pancreaticoduodenectomy...

Eligibility Criteria

Inclusion

  • Male or female, 18 to 75 years of age, inclusive.
  • Patients have a diagnosis of benign and malignant diseases of the pancreatic head and periampullary region and requiring pancreaticoduodenectomy.
  • Patients have not been treated with any anticancer medications and immunotherapy prior to surgery
  • Patients have not been accompanied by serious physical diseases of heart, lung, brain, etc., and can generally tolerable for surgery.
  • Ability to understand and the willingness to sign a written informed consent document.

Exclusion

  • Female subjects who are pregnant or breastfeeding.
  • Patients scheduled to undergo pancreatogastrostomy.
  • Patients whose pancreatic duct cannot be located.
  • Patients with history of previous pancreatic surgery, server acute or chronic disease or surgical contraindication.
  • Patients with HIV-infectious or other AIDS-related disease.
  • Patients have any condition that in the judgement of the Investigators would make the subject inappropriate for entry into this study.

Key Trial Info

Start Date :

June 24 2019

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

July 1 2021

Estimated Enrollment :

960 Patients enrolled

Trial Details

Trial ID

NCT03767959

Start Date

June 24 2019

End Date

July 1 2021

Last Update

March 4 2020

Active Locations (1)

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1

Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology

Wuhan, Hubei, China, 430030