Status:
RECRUITING
APACHE Cohort (A Psoriatic Arthritis CoHort)
Lead Sponsor:
Assistance Publique - Hôpitaux de Paris
Conditions:
Cohort Study
Psoriatic Arthritis
Eligibility:
All Genders
18-60 years
Brief Summary
Psoriatic arthritis (PsA) is a chronic inflammatory rheumatic disease, belonging to the wide spectrum of spondyloarthritis, but with the particularity to be associated with personal psoriasis or famil...
Detailed Description
Method:APACHE is a prospective national multicentre (29) cohort including and following during 10 years patients with a first peripheral arthritis in the past year, attributing to a PsA according to t...
Eligibility Criteria
Inclusion
- Women or men aged from 18 to 60 inclusive
- First episode of peripheral arthritis in the last 12 months, authenticated by a rheumatologist
- Psoriasis diagnosed by a practitioner or family history of psoriatic arthritis (first-degree relative \[parent or sibling\] or second degree relative)
- Arthritis most likely recognized as a psoriatic arthritis by a rheumatologist (diagnostic confidence score : ≥ 7 out of 10)
- Signed informed consent form
- Affiliation to a social security system
Exclusion
- Formal diagnostic of inflammatory rheumatism other than psoriatic arthritis
- Treatment or history of treatment with a biomedicine
- Patient receiving csDMARDS or apremilast treatment for 1 year or more
- Patient having received csDMARDS or apremilast treatment during the last 12 months
- Oral steroids in the last 4 weeks, above 10 mg/d of prednisone or with modified dosage
- intravenous or intra articular steroids in the last 4 weeks
- IRM contraindication
- Cognitive, mental or psychic disorders impeding protocol accomplishment
- Difficulties with French language understanding
- Patient under tutorship or curatorship
- Pregnancy
Key Trial Info
Start Date :
February 12 2020
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
March 1 2034
Estimated Enrollment :
425 Patients enrolled
Trial Details
Trial ID
NCT03768271
Start Date
February 12 2020
End Date
March 1 2034
Last Update
November 18 2023
Active Locations (3)
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1
Henri-Mondor Hospital
Créteil, France, 94000
2
Lapeyronie Hospital
Montpellier, France, 34090
3
Saint Joseph Hospital
Paris, France, 75014