Status:
COMPLETED
Comparison of the Efficacy of Intravenous Dexketoprofen and Paracetamol in the Treatment of Sore Throat
Lead Sponsor:
Pamukkale University
Conditions:
Sore Throat
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
Currently, paracetamol and nonsteroidal antiinflammatory drugs are widely used by emergency physicians in Turkey for the treatment of sore throat. The objective of the study is compare the efficacy of...
Detailed Description
This is the randomized double blinded clinical trial to compare the efficacy of these two drugs in this clinical setting. A randomized clinical trial was conducted in the Emergency Department (ED) of ...
Eligibility Criteria
Inclusion
- Patients with sore throat less than three days
- Patients with at least one of the following:
- According to the throat pain scale, patients with moderate-severe pain,
- At least 1 upper respiratory tract infection (URTI) symptom according URTI questionare,
- Objective findings of pharyngeal inflammation (Tonsillopharyngitis evaluation score ≥5),
- 60 mm or more according to the sore throat sensitivity scale (STSS),
- 50 mm and above according to difficulty swallowing scale (DSS),
- 33 mm and above according to the swollen throat scale (SwoTS)
Exclusion
- Patients use analgesic last 12 hours
- Patients with severe liver, kidney,pulmonary and cardiac heart failure
- To be Pregnancy and breast-feeding Patients of childbearing age who are not using a birth control method
- Patients with an allergy trait (paracetamol and dexketoprofen) Illiterates
- Patients with vision problems
- Patients use antibiotics last 24 hours
- Patients use kinolons last 7 days
- Patienst use lozange,throat spray or menthol containing products last 4 hours
- Hemodynamically unstable patients,Patients with renal transplantation
- Patients with glucose 6 phosphate dehydrogenase (G6PD) deficiency
- Patients with non-controlled hypertension
- Patients with a history of cerebrovascular disease
- Patients with Wolff-Parkinson-White syndrome or accompanying arrhythmias associated with conductive stimulus delivery in the heart
Key Trial Info
Start Date :
December 1 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 30 2018
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT03768882
Start Date
December 1 2017
End Date
July 30 2018
Last Update
December 10 2018
Active Locations (1)
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1
Pamukkale University
Denizli, Turkey (Türkiye), 20070