Status:
RECRUITING
Preoperative Teriparatide Use on Insertional Torque of Pedicle Screws for Lumbar Fusion Surgery
Lead Sponsor:
The University of Hong Kong
Conditions:
Osteoporosis
Fusion of Spine, Lumbar Region
Eligibility:
All Genders
40-100 years
Phase:
NA
Brief Summary
This project aims to investigate any difference of insertional torque strength for osteoporotic patients with preoperative 1-month teriparatide injections versus those without. The increased insertion...
Detailed Description
For this project, adult patients (\>40 years) undergoing lumbar spinal fusion will be randomized to undergo teriparatide treatment for 1 month prior to surgery. Patients will have their baseline BMD a...
Eligibility Criteria
Inclusion
- Patients must be osteoporotic: baseline BMD assessed by DEXA scan must be considered as osteoporotic (\>2.5 SD from sex-matched young adult, or previous vertebral and/or femoral fractures) and indicated for spinal fusion surgery
Exclusion
- Paget disease of bone, high laboratory tests for serum alkaline phosphatase or calcium, previous radiation treatment or fusion surgery to lumbar spine, bone tumors, metabolic bone disease, and hypersensitivity to teriparatide
Key Trial Info
Start Date :
March 1 2019
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 30 2025
Estimated Enrollment :
192 Patients enrolled
Trial Details
Trial ID
NCT03770338
Start Date
March 1 2019
End Date
June 30 2025
Last Update
December 6 2024
Active Locations (3)
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1
Jason Pui Yin Cheung
Hong Kong, Please Select An Option Below, Hong Kong
2
Duchess of Kent Children's Hospital
Hong Kong, Hong Kong
3
Queen Mary Hospital
Hong Kong, Hong Kong