Status:

COMPLETED

Wearable Skin Sensors to Assess Nocturnal Scratch Behavior

Lead Sponsor:

Northwestern University

Collaborating Sponsors:

Pfizer

Conditions:

Atopic Dermatitis

Eligibility:

All Genders

2+ years

Brief Summary

Pilot study of flexible and wearable sensor to monitor nocturnal scratching behavior

Detailed Description

Present an advanced flexible, and wearable sensor intimately coupled to the skin that can measure the full spectrum of relevant physiological parameters associated with atopic dermatitis including scr...

Eligibility Criteria

Inclusion

  • Participants with mild to moderate atopic dermatitis ages 2 years or older. This will be determined by clinical diagnosis of AD according to the Hanifin and Rajka criteria with a baseline Investigators Global Assessment score of mild (2) or moderate (3)
  • Systemic therapy use (e.g. oral corticosteroid, cyclosporine, methotrexate, phototherapy) within 28 days of subject enrollment
  • Topical corticosteroid use or topical calcineurin inhibitor use within 14 days of subject enrollment
  • Willingness and ability to set up an infrared video camera nightly
  • Willing to apply topical crisaborole twice daily to affected atopic dermatitis areas of the body

Exclusion

  • Active skin or systemic infection
  • Inability to operate a smartphone or video camera
  • Active atopic dermatitis on he dorsum of the hand or suprasternal notch

Key Trial Info

Start Date :

April 18 2019

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

August 24 2022

Estimated Enrollment :

23 Patients enrolled

Trial Details

Trial ID

NCT03770858

Start Date

April 18 2019

End Date

August 24 2022

Last Update

October 13 2023

Active Locations (1)

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1

Northwestern University

Chicago, Illinois, United States, 60611