Status:
COMPLETED
Sevoflurane vs Propofol Effect on Endothelial Damage Markers After Knee Ligament Surgery.
Lead Sponsor:
University of Chile
Conditions:
Ischemia Reperfusion Injury
Eligibility:
All Genders
18-60 years
Phase:
NA
Brief Summary
Endothelial damage has been reported after ischemia-reperfusion events. This can be characterized by measurements of glycocalyx and endothelial components that are released to blood after the insult. ...
Detailed Description
To study the anesthetics effect on the endothelial damage induced by Ischemia-reperfusion (IR) in knee-ligament surgery, we will perform a randomized controlled clinical trial comparing the concentrat...
Eligibility Criteria
Inclusion
- American Society of Anesthesiologists Classification (ASA Class) I and II
- Elective knee ligament surgery
- Use of a femoral tourniquet
Exclusion
- Allergies to egg or soya
- Previous history of critical events during surgery and perioperative period
- Patients at risk of hyperthermia malignant
- Patients with 3 or more predictor of difficult airway management
Key Trial Info
Start Date :
December 20 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 11 2019
Estimated Enrollment :
16 Patients enrolled
Trial Details
Trial ID
NCT03772054
Start Date
December 20 2018
End Date
December 11 2019
Last Update
December 12 2019
Active Locations (1)
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1
Hospital Clínico de la Universidad de Chile
Independencia, Santiago Metropolitan, Chile, 8380456