Status:
COMPLETED
Effect of Sevoflurane and Propofol on Hepato-splanchnic Pressure and Flow During Hepatobiliary Surgery
Lead Sponsor:
University Hospital, Ghent
Conditions:
General Anesthesia
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
Blood loss in hepatobiliary surgery is correlated with an increase in postoperative complications (e.g. transfusion related lung injury and tumor recurrence) and reduced longterm survival. To reduce m...
Detailed Description
All patients receive standardized anesthesia care for hepato-biliary surgery according to the existing anesthesia protocol. The type of anaesthesia will be randomized : propolipid (TIV) or sevorane(in...
Eligibility Criteria
Inclusion
- Adult ≥ 18 years (Female or Male)
- ASA I - II - III
- Able to comprehend, sign and date the written informed consent document to participate in the clinical trial.
- Scheduled for hepato-biliary surgery.
Exclusion
- Allergy for the medication
- Renal insufficiency (SCr \> 2 mg/dl)
- Severe heart failure (EF \< 25%)
- Hemodynamic instable patients
- Arterial fibrillation
- Sepsis
- BMI \> 40
- Severe coagulopathy (INR \> 2)
- Thrombocytopenia (\< 80 x 10³ /µL)
- History of severe postoperative nausea \& vomiting
Key Trial Info
Start Date :
June 8 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 4 2018
Estimated Enrollment :
29 Patients enrolled
Trial Details
Trial ID
NCT03772106
Start Date
June 8 2017
End Date
December 4 2018
Last Update
December 11 2018
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University Hospital Ghent
Ghent, Oost-Vlaanderen, Belgium, 9000