Status:
TERMINATED
Use of Beetroot Juice to Protect Against Postoperative Ileus (POI) Following Colorectal Surgery: a Pilot Study.
Lead Sponsor:
University Hospital, Ghent
Collaborating Sponsors:
University Ghent
Conditions:
Postoperative Ileus
Eligibility:
All Genders
18-95 years
Phase:
NA
Brief Summary
The BEET IT study investigates the possible protective effect of beetroot juice on POI following colorectal surgery in (partially) blinded single-center phase 2 randomized trial (pilot study).
Detailed Description
Postoperative ileus (POI) is a transient impairment of gastrointestinal motility following abdominal surgery, which leads to increased morbidity, prolonged hospitalization and increased healthcare cos...
Eligibility Criteria
Inclusion
- • All patients undergoing colonic or upper rectum laparoscopic surgery.
Exclusion
- Pregnancy or breast feeding
- Psychiatric pathology capable of affecting comprehension and judgment faculty
- History of metastatic disease
- History of prior abdominal bowel surgery
- Abdominal radiation treatment
- Chronic constipation (defined as two or fewer bowel movements per week)
- Gut motility influencing agents (e.g. tricyclic antidepressants, chronic use of laxatives)
- Frequent use of mouthwash, as this affects the enterosalivary circulation of nitrate
- Current use of broad-spectrum antibiotics, which will affect the oral flora and likely affect the nitrate reductase activity
- More than one bowel anastomosis during this surgery
Key Trial Info
Start Date :
January 15 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 25 2019
Estimated Enrollment :
12 Patients enrolled
Trial Details
Trial ID
NCT03772444
Start Date
January 15 2018
End Date
May 25 2019
Last Update
January 20 2023
Active Locations (1)
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1
Ghent University Hospital
Ghent, Belgium, 9000