Status:

COMPLETED

EUS-RFA for Unresectable Pancreatic Ductal Adenocarcinoma

Lead Sponsor:

First People's Hospital of Hangzhou

Conditions:

Pancreatic Adenocarcinoma Non-resectable

Eligibility:

All Genders

20-80 years

Phase:

NA

Brief Summary

the study evaluate the efficacy and safety of EUS-RFA using Habib EUS-RFA catheter with a prospective randomised trial in patients with inoperable PDAC.

Detailed Description

The five year survival for pancreatic ductal adenocarcinoma (PDAC) is less than 5% in spite of the advances in management of cancers in the last few decades. Endobiliary application of radiofrequency ...

Eligibility Criteria

Inclusion

  • Patients in the age group 20 to 80 years
  • A cytological or histological diagnosis of inoperable PDAC based on multidisciplinary review of cross sectional imaging and cytology or histology results.
  • Patients who have been deemed unfit for surgical resection of the PDAC subjects who are fit for surgical resection but have declined surgery will also be considered for the study
  • PDAC patients presenting with jaundice to be considered after a successful biliary drainage
  • Patients ought to be fit enough to be considered for the study (ECOG performance status 0, 1 or 2)
  • Patients capable of giving informed consent

Exclusion

  • Inability to give informed consent
  • Pregnancy or breast feeding
  • ECOG performance status 3 or 4
  • Life expectancy less than 3 months
  • Patients with distant metastases or malignant ascites

Key Trial Info

Start Date :

December 20 2018

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 16 2021

Estimated Enrollment :

38 Patients enrolled

Trial Details

Trial ID

NCT03772756

Start Date

December 20 2018

End Date

August 16 2021

Last Update

August 30 2021

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Jianfeng Yang

Hangzhou, Zhejiang, China, 310006

2

Hangzhou First People's Hospital

Hangzhou, Zhejiang, China, 31006