Status:
UNKNOWN
Timing of Transcranial Direct Current Stimulation (tDCS) Combined With Speech and Language Therapy (SLT)
Lead Sponsor:
Shirley Ryan AbilityLab
Collaborating Sponsors:
National Institute on Disability, Independent Living, and Rehabilitation Research
Conditions:
Aphasia
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
Aphasia is an acquired (typically left-hemisphere) multi-modality disturbance of language that impacts around 2 million people in the USA. Aphasia impacts language production and comprehension as well...
Detailed Description
tDCS Implementation: 2mA of direct current for 20 minutes will be delivered using a constant current stimulator via two electrodes in saline soaked sponges. To stimulate the left angular gyrus, a cat...
Eligibility Criteria
Inclusion
- Men or women with diagnosis of fluent or non-fluent aphasia subsequent to a left-hemisphere infarct(s) that is confirmed by a MRI or CT scan
- Aphasia quotient on the WAB of 35-85
- At least 6 months post onset of aphasia (this is beyond the stage of spontaneous recovery)
- 18- 80 years of age
- Premorbidly fluent in English
- Premorbidly right-hand dominant per the Edinburg Handedness Inventory
- Visual acuity of 20/40 corrected
- Auditory acuity no worse than 30 dB HL on pure tone testing, aided in the better ear.
- Education greater than 12th grade
Exclusion
- Any other neurological condition (other than cerebral vascular disease) that could impact language and cognition such as Alzheimer's disease, Parkinson's disease, primary progressive aphasia, and traumatic brain injury
- Active substance use
- Individuals with epilepsy
Key Trial Info
Start Date :
April 3 2019
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2022
Estimated Enrollment :
48 Patients enrolled
Trial Details
Trial ID
NCT03773406
Start Date
April 3 2019
End Date
December 1 2022
Last Update
July 26 2022
Active Locations (1)
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1
Shirley Ryan AbilityLab
Chicago, Illinois, United States, 60611