Status:
UNKNOWN
Chemical Peels and Fractional Laser on IGF-1 Levels in Skin
Lead Sponsor:
Massachusetts General Hospital
Conditions:
Skin Cancer
Eligibility:
All Genders
55+ years
Phase:
NA
Brief Summary
The purpose of this study is to evaluate the impact of fractional laser versus chemical peels on IGF-1 levels in skin.
Detailed Description
This study is designed to assess the feasibility of using a fractional non ablative laser and chemical peels to wound skin, and thereby elicit a change in IGF-1. Our hypothesis is that fractional non ...
Eligibility Criteria
Inclusion
- Male and female subjects \>55 years old
- Fitzpatrick type I-II
- Able to provide informed consent.
- Cutaneous photodamage of 3 or above on the Larnier photodamage scale (see Appendix).
Exclusion
- Prior laser or peel treatment in the area evaluated in the current study in the past year.
- Currently taking immunosuppressant medications known to interfere wound healing or anti-inflammatory medications (such as NSAIDs, or steroids).
- Subjects who have underlying diseases that could alter wound healing response (such as Diabetes).
- Currently taking insulin.
- History of substance abuse, mental dysfunction, or other factors limiting ability to cooperate with study.
- History of abnormal scarring such as Keloids.
- History of vitiligo.
- Allergy or sensitivity or allergy to topical anesthesia
- Inability to use sunscreen.
- History of smoking in the last 10 years
- Scar or prior surgery in the area of treatment.
- Use of isotretinoin in the prior 6 months
- Subjects who have bleeding disorders or who are taking anticoagulants
Key Trial Info
Start Date :
December 1 2019
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 1 2021
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT03775031
Start Date
December 1 2019
End Date
July 1 2021
Last Update
October 22 2020
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Massachusetts General Hospital Clinical Unit for Research Trials and Outcomes in Skin
Boston, Massachusetts, United States, 02114