Status:

UNKNOWN

Neuro-cognitive Impact of Juvenile Obesity

Lead Sponsor:

University Hospital, Bordeaux

Collaborating Sponsors:

Equipe NeuroImagerie et Cognition Humaine CNRS UMR 5287 - INCIA

University of Bordeaux

Conditions:

Pediatric Obesity

Behavior and Behavior Mechanisms

Eligibility:

MALE

12-17 years

Phase:

NA

Brief Summary

Recent studies indicate that obese teenagers exhibit memory disturbances. Adolescence represents a crucial period in the development of the hippocampus and the amygdala, necessary for the implementati...

Detailed Description

Obesity increases the prevalence of cognitive impairment. In particular, it can promote disturbances of contextual memory dependent on the hippocampus. Obesity is also associated with negative emotion...

Eligibility Criteria

Inclusion

  • Experimental group: 12-17 years old boys, BMI\>30 (according to IOTF), right-handed, French secondary school, beneficiary of social security, consent of the holders of parental authority.
  • Control group: 12-17 years old boys, BMI\<25 (according to IOTF), right-handed, French secondary school, beneficiary of social security, consent of the holders of parental authority.

Exclusion

  • Adolescent with pubertal stage of Tanner \<2
  • Adolescent with known visual or auditory difficulties
  • Adolescent with a known chronic pathology requiring medication
  • Adolescent with psychotic, neurodevelopmental or substance use disorder
  • Adolescent who may have a contraindication to the MRI examination (presence in the body of metallic prostheses, pacemaker, metal chips, claustrophobia).

Key Trial Info

Start Date :

December 12 2018

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 12 2020

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT03776513

Start Date

December 12 2018

End Date

December 12 2020

Last Update

December 14 2018

Active Locations (1)

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1

Bordeaux University Hospital

Bordeaux, France, 33079