Status:
COMPLETED
Effect of Propofol Midazolam on Cerebral Oxygenation and Metabolism During Clipping of Ruptured Cerebral Aneurysm
Lead Sponsor:
Mansoura University
Conditions:
Ruptured Cerebral Aneurysm
Eligibility:
All Genders
20-60 years
Phase:
NA
Brief Summary
Despite the theoretical benefits of i.v. agents, volatile agents remain popular. In a study comparing desflurane, isoflurane, and sevoflurane in a porcine model of intracranial hypertension, at equipo...
Detailed Description
The aim of this study is to evaluate the cerebral hemodynamics and global cerebral oxygenation as well as the systemic hemodynamic changes using midazolam and propofol as total intravenous anesthetics...
Eligibility Criteria
Inclusion
- American Society of Anesthesiologists physical status III or IV.
Exclusion
- Morbid obese patients.
- Severe or uncompensated cardiovascular diseases
- Severe or decompensated renal diseases
- Severe or decompensated hepatic diseases
- Severe or decompensated endocrinal diseases.
- Pregnancy
- Postpartum
- Lactating females
- Allergy to one of the agents used.
- Severely altered consciousness level.
- Sitting or prone position during surgery.
Key Trial Info
Start Date :
December 18 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 10 2020
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT03778723
Start Date
December 18 2018
End Date
January 10 2020
Last Update
September 4 2020
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Sherif A Mousa
Al Mansurah, DK, Egypt, 050