Status:

UNKNOWN

Vaginal Progesterone Versus 17-Alpha-Hydroxyprogesterone Caproate in Placenta Previa

Lead Sponsor:

Aswan University Hospital

Conditions:

Placenta Previa

Eligibility:

FEMALE

18-45 years

Phase:

NA

Brief Summary

Purpose to evaluate the effects of Vaginal Progesterone versus 17-Alpha-Hydroxyprogesterone Caproate for prevention of Emergent Cesarean Delivery in Asymptomatic Pregnant Women with Placenta Previa

Detailed Description

The study will be a randomized open-label clinical trial conducted at a tertiary university hospital outpatient clinic and some private settings at Aswan governorate, Egypt, between January 2019 and M...

Eligibility Criteria

Inclusion

  • Gestational age 26-28 weeks of gestation.
  • Definite and reliable diagnosis of placenta previa (defined as the presence of a placenta within 2 cm of the internal os), using a transvaginal ultrasound scan

Exclusion

  • Multiple pregnancies.
  • Women at high risk of preterm labor e.g. history of spontaneous preterm labor or preterm prelabour rupture of the membranes (PPROM).
  • Severe antepartum hemorrhage and/or hemodynamic instability that necessitates urgent -intervention and delivery.
  • Women who have been maintained on progestin therapy since early pregnancy for whatever reason.

Key Trial Info

Start Date :

January 1 2019

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

April 1 2022

Estimated Enrollment :

400 Patients enrolled

Trial Details

Trial ID

NCT03779451

Start Date

January 1 2019

End Date

April 1 2022

Last Update

February 15 2019

Active Locations (1)

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1

Aswan University

Aswān, Egypt, 81528