Status:

COMPLETED

Dopamine and Norepinephrine Infusion With Restricted Hydration

Lead Sponsor:

Ain Shams University

Conditions:

Renal Function Test, Urine Output, Lactate Level

Eligibility:

All Genders

18-75 years

Phase:

NA

Brief Summary

This study was designed to assess the effect of adding dopamine infusion in addition to restrictive hydration combined with noradrenaline infusion on intraoperative serum lactate levels as an indicato...

Detailed Description

One hundred and twenty patients were randomly assigned into three groups (dopamine norepinephrine group, restrictive hydration group and liberal hydration group) undergoing open abdominal procedures (...

Eligibility Criteria

Inclusion

  • All patients with American Society of Anesthesiologists (ASA) physical status I or II
  • Age range from 18-80 years scheduled to either radical cystectomy or hemicolectomy were contained in the study.

Exclusion

  • Patients with coagulopathies,
  • Hepatic dysfunction (prothrombin ratio \<50%),
  • Renal dysfunction,
  • Congestive heart failure (New York Heart Association scores ≥3),
  • Contraindications for epidural analgesia (e.g. patient refusal, local infection or coagulopathy), and peripheral vascular disease.

Key Trial Info

Start Date :

April 9 2017

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 15 2018

Estimated Enrollment :

120 Patients enrolled

Trial Details

Trial ID

NCT03780686

Start Date

April 9 2017

End Date

December 15 2018

Last Update

December 20 2018

Active Locations (1)

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1

Ain Shams University

Cairo, Egypt, 11233