Status:

COMPLETED

Phase 1 Study in Patients With Advanced and/or Refractory Solid Malignancies to Evaluate the Safety of ATOR-1015

Lead Sponsor:

Alligator Bioscience AB

Conditions:

Solid Tumor

Neoplasms

Eligibility:

All Genders

18+ years

Phase:

PHASE1

Brief Summary

The aim of the study is to investigate the safety and tolerability of ATOR-1015 when administered as repeated intravenous infusions to patients with advanced and/or refractory solid malignancies.

Eligibility Criteria

Inclusion

  • Major
  • Diagnosis of advanced and/or refractory solid malignancy
  • Eastern Cooperation Oncology Group (ECOG) performance status of 0 or 1
  • Life expectancy of at least 3 months
  • Major

Exclusion

  • Organ transplant recipient
  • Active autoimmune disorder
  • Other malignancy

Key Trial Info

Start Date :

January 30 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 3 2021

Estimated Enrollment :

33 Patients enrolled

Trial Details

Trial ID

NCT03782467

Start Date

January 30 2019

End Date

March 3 2021

Last Update

August 18 2022

Active Locations (5)

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Page 1 of 2 (5 locations)

1

Phase 1 Unit, Department of Oncology, Rigshospitalet

Copenhagen, Denmark, DK-2100

2

Center for Cancer Research, Department of Oncology, Herlev Hospital

Herlev, Denmark, DK-2730

3

Kliniska Prövningsenheten, Kliniska Studier Sverige - Forum Söder, Skånes Universitetssjukhus

Lund, Sweden, SE-221 85

4

Centrum för Kliniska Cancerstudier (CKC), Fas 1-enheten, Karolinska Universitetssjukhuset

Solna, Sweden, SE-171 64