Status:
COMPLETED
Brain, Appetite, Teens, and Exercise
Lead Sponsor:
Children's Mercy Hospital Kansas City
Collaborating Sponsors:
University of Kansas Medical Center
Conditions:
Energy Balance
Appetitive Behavior
Eligibility:
All Genders
14-17 years
Phase:
NA
Brief Summary
The long-term goal is to develop effective, evidence-based lifestyle interventions to prevent and treat childhood obesity and related co-morbidities. The short-term goal, and the purpose of this appli...
Detailed Description
Specific Aim 1: To identify associations between neural, psychological, and hormonal appetite control pathways using subjective and objective measures of appetite and neurocognitive assessments of rew...
Eligibility Criteria
Inclusion
- Inclusion Criteria
- Overweight/obese (BMI ≥85th to \<99th percentile for age and sex)
- Weight stable
- Ages 14-17
- No meds that may alter metabolism
- Sedentary (\<20 min/day exercise)
- At risk for T2D, according to American Diabetes Association (ADA) criteria:
- family history of T2D in first- or second- degree relative
- Race/ethnicity (Native American, African American, Latino, Asian American, Pacific Islander)
- Signs of insulin resistance
- Maternal history of diabetes for gestational diabetes during child's gestation
- Willing to participate in an exercise program
- Willing to provide permission/assent
- Exclusion Criteria:
- BMI \<85th percentile for age and sex
- Weight not stable
- Age \<14 or \>17
- On meds that may alter metabolism
- Active (\>20 min/day exercise)
- Not at risk for T2D, according to American Diabetes Association (ADA) criteria (see above)
- Not willing to participate in an exercise program
- Not willing to provide permission/assent
Exclusion
Key Trial Info
Start Date :
September 1 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 10 2019
Estimated Enrollment :
19 Patients enrolled
Trial Details
Trial ID
NCT03783390
Start Date
September 1 2018
End Date
August 10 2019
Last Update
May 14 2020
Active Locations (1)
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1
Children's Mercy Kansas City
Kansas City, Missouri, United States, 64114