Status:

COMPLETED

Type 2 Diabetic Patients Maintained on Statin Therapy

Lead Sponsor:

Damanhour University

Collaborating Sponsors:

Tanta University

Conditions:

Dyslipidemia Associated With Type II Diabetes Mellitus

Eligibility:

All Genders

35-70 years

Phase:

PHASE4

Brief Summary

Patients with diabetes mellitus (DM) are at increased risk of atherosclerotic cardiovascular disease (ACVD). The achievement of the LDL-C target with statins for the reduction of ACVD risk is recommen...

Detailed Description

a prospective, double blind trial, conducted between January 2018 and January 2020. Participants were enrolled if they had moderate cardiovascular risk (Framingham risk score of 10-20%), in other word...

Eligibility Criteria

Inclusion

  • type II diabetic patients with hypercholesterolemia

Exclusion

  • liver impairment,
  • renal insufficiency,
  • coronary artery disease,
  • metabolic disorders,
  • type I diabetes,
  • autoimmune diseases, cancer, infection,
  • use of anti-inflammatory drugs,
  • recent major surgery,
  • weight-loss or modified anti-hypertensive medications 12 weeks or less prior to enrolment,
  • ongoing or previous use of lipid-lowering medications (including other statins, fibric acid derivatives, nicotinic acid, cholestyramine, ezetimibe or omega-3 fatty acids) and contraindications to the use of statins.

Key Trial Info

Start Date :

January 1 2018

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 31 2020

Estimated Enrollment :

160 Patients enrolled

Trial Details

Trial ID

NCT03784703

Start Date

January 1 2018

End Date

January 31 2020

Last Update

January 5 2021

Active Locations (1)

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1

Tanta University Hospital

Tanta, El-Gharbia, Egypt, 31527