Status:
RECRUITING
Comparing Laparoscopic and Open Surgery for Pancreatic Carcinoma
Lead Sponsor:
Tongji Hospital
Collaborating Sponsors:
Shandong Provincial Hospital
The Second Hospital of Hebei Medical University
Conditions:
Pancreatic Carcinoma
Laparoscopic
Eligibility:
All Genders
18-75 years
Phase:
NA
Brief Summary
Background: Pancreatic cancer (PC) is one of the most aggressive malignant neoplasms with poor outcomes. Pancreatoduodenectomy (PD) is the only curative treatment for PC. Minimally invasive surgery ha...
Eligibility Criteria
Inclusion
- Age between 18 years and 75 years.
- Histologically confirmed PDAC or clinically diagnosed PDAC by an MDT without histopathologic evidence.
- Patients feasible to undergo both LPD and OPD according to MDT evaluations.
- Patients understanding and willing to comply with this trial.
- Provision of written informed consent before patient registration.
- Patients meeting the curative treatment intent in accordance with clinical guidelines.
Exclusion
- Patients with distant metastases, including peritoneal, liver, distant lymph node metastases, and involvement of other organs.
- Patients requiring left, central or total pancreatectomy or other palliative surgery.
- Preoperative American Society of Anaesthesiologists (ASA) score ≥ 4.
- History of other malignant disease.
- Pregnant or breast-feeding women.
- Patients with serious mental disorders.
- Patients treated with neoadjuvant therapy.
- Patients with vascular invasion and requiring vascular resection as evaluated by the MDT team according to abdominal imaging data.
- Body mass index \> 35 kg/m2.
- Patients participating in any other clinical trials within 3 months.
Key Trial Info
Start Date :
March 1 2019
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 1 2027
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT03785743
Start Date
March 1 2019
End Date
May 1 2027
Last Update
March 2 2022
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Department of Biliary and Pancreatic Surgery, Tongji Hospital, Affiliated Tongji Medical College, Huazhong University of Science and Technology
Wuhan, Hubei, China, 430030