Status:
COMPLETED
Virtual Reality- Working Memory Retraining
Lead Sponsor:
University of California, San Francisco
Collaborating Sponsors:
San Francisco VA Health Care System
Conditions:
Alcohol Use Disorder
Mild Traumatic Brain Injury
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
This study will establish the acceptability and feasibility of enrolling and retaining heavy drinking Veterans with mild traumatic brain injury (mTBI) in an 8-week, randomized cross-over design trial ...
Detailed Description
The investigators will employ a physically active VR working memory retraining (VR-WMR) regimen utilizing components of Blue Goji VR Active Gaming. The synthesis of physical activity and an enriched V...
Eligibility Criteria
Inclusion
- must report "heavy" drinking by NIH/NIAAA criteria (\>7 drinks/week for women; \>14 drinks/week for men) for at least one week in the last 90 days
- must meet moderate to severe criteria for current (past year) alcohol use disorder (AUD) by DSM-5
- must express a desire to reduce, stop, or maintain cessation of alcohol use
- must report a history of TBI as defined by American Congress of Rehabilitation Medicine (ACRM), in the chronic, stable phase of recovery (\>6 months from injury)
Exclusion
- Unstable medical or psychiatric disorders judged to be unstable in the clinical judgment of the PI
- Current or past history of intrinsic cerebral tumors, HIV infection, cerebrovascular accident, aneurysm, arteriovenous malformations, myocardial infarction, cerebrovascular or peripheral vascular disease, type-1 diabetes, any cardiac, hepatic or renal diseases/disorders, surgical implantation of neurostimulators or cardiac pacemakers, medically diagnosed chronic obstructive pulmonary disease, demyelinating and neurodegenerative diseases, history of seizure disorder, and/or any physical disability making it impossible to use exercise equipment
- No female participant will be pregnant or attempting to conceive
- Concurrent participation in an AUD, cognitive training, or exercise study
- Must not require acute medical detoxification from alcohol (CIWA-AD \> 11) within the past week prior to study entry
- Subjects who, in the opinion of the investigator, are otherwise unsuitable for a study of this type will be excluded
Key Trial Info
Start Date :
February 1 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 31 2020
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT03786276
Start Date
February 1 2019
End Date
March 31 2020
Last Update
May 4 2020
Active Locations (1)
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1
VA Medical Center San Francisco
San Francisco, California, United States, 94121