Status:

COMPLETED

Reduction of Radiation Dose and Contrast Use During Cryoballoon Pulmonary Vein Isolation

Lead Sponsor:

University of Texas Southwestern Medical Center

Collaborating Sponsors:

Medtronic

Conditions:

Atrial Fibrillation

Eligibility:

All Genders

18-70 years

Phase:

NA

Brief Summary

This is a multi-site, randomized, investigator-initiated pilot study to evaluate the efficacy of investigational techniques to reduce fluoroscopy time or radiation dose and the amount of radio opaque ...

Detailed Description

Surgical and catheter based technologies target triggers that initiate atrial fibrillation located in the pulmonary veins (PV). In order to isolate these triggers, radiofrequency energy or freezing is...

Eligibility Criteria

Inclusion

  • Inclusion Criteria:
  • Paroxysmal atrial fibrillation refractory to treatment with anti-arrhythmic drugs
  • Must be able to undergo pre-operative cardiac CT angiogram or cardiac MRI to define pulmonary vein anatomy.
  • Exclusion criteria:
  • Planned use of radiofrequency cardiac ablation
  • Presence of a cardiac implantable electronic device
  • Conditions where manipulation of the catheter would be unsafe such as intracardiac thrombus
  • Patients with active systemic infections
  • Patients with cryoglobulinemia
  • Pregnant and/or breast-feeding females are excluded from this study.

Exclusion

    Key Trial Info

    Start Date :

    June 1 2015

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    December 20 2016

    Estimated Enrollment :

    1 Patients enrolled

    Trial Details

    Trial ID

    NCT03786822

    Start Date

    June 1 2015

    End Date

    December 20 2016

    Last Update

    December 26 2018

    Active Locations (1)

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    Page 1 of 1 (1 locations)

    1

    University of Texas Southwestern

    Dallas, Texas, United States, 75390