Status:
COMPLETED
Effect of Lidocaine Plus Dexmedetomidine Infusion on PONV
Lead Sponsor:
Xu Siqi
Conditions:
Lidocaine
Dexmedetomidine
Eligibility:
FEMALE
40-55 years
Phase:
NA
Brief Summary
BACKGROUND: Few researches have manifested that intravenous (IV) lidocaine or dexmedetomidine decreased the incidence of postoperative nausea and vomiting (PONV). The investigators investigated whethe...
Eligibility Criteria
Inclusion
- American Society of Anesthesiologists (ASA) physical statusⅠand Ⅱ
- Aged 40-55 years
- Scheduled for elective laparoscopic hysterectomy
Exclusion
- History of allergy to local anesthetics
- Severe respiratory disease
- Renal or hepatic insufficiency
- History of preoperative opioids medication and psychiatric
- preoperative bradycardia
- preoperative atrioventricular block
- Subjects who experienced severe hypotension (mean arterial pressure \[MAP\] \<60 mmHg) or bradycardia (heart rate \[HR\] \<40 bpm), urticaria, or arrhythmia during lidocaine and dexmedetomidine infusion period
Key Trial Info
Start Date :
January 1 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2018
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT03788018
Start Date
January 1 2018
End Date
December 1 2018
Last Update
January 8 2019
Active Locations (1)
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1
Department of Anqing Hospital Anesthesiology
Anqing, Anhui, China, 246000